Myxedema (British English: Myxoedema) is a term used synonymously with severe hypothyroidism. It is also to describe a dermatological change that can occur in hypothyroidism, and some forms of hyperthyroidism. This article discusses the dermatological changes.
Random House, Inc. is the largest general-interest trade book publisher in the world. It has been owned since 1998 by the German private media corporation Bertelsmann and has become the umbrella brand for Bertelsmann book publishing. Random House also has a movie production arm, Random House Films, of which the most recent release was One Day. The company is also creating story content for media including video games, social networks on the web, and mobile platforms.